Acetic Acid → HCID 19909838, compound

Participants

Reaction Steps

To a mixture of 1 ml of 47% hydrobromic acid and 1 ml of acetic acid was added 100 mg of 3-(1-imidazolylmethyl)-2-pyrazolin-5-one and stirred under reflux for 4 hours. After removing the solvent by evaporating, the residue was adjusted in pH to 4 by adding water and an aqueous NaHCO3 solution and then extracted with a mixed solvent of chloroform and ethanol (4:1).

Provenance & Evidence