Piperidine-1-propylamine → HCID 20071565, compound

HRID 981414Notes

Reaction equation

HRID 981414 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1.[C:11]([O:19][C:20]1[CH:28]=[C:27]([O:29][C:30](=O)[C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:26]=[CH:25][C:21]=1[C:22](O)=[O:23])(=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:11]([O:19][C:20]1[CH:28]=[C:27]([O:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:26]=[CH:25][C:21]=1[C:22]([NH:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1)=[O:23])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 19049Piperidine-1-propylamineHCID 15486385HCID 15486385, compound

Product 1

HCID 20071565HCID 20071565, compoundYield 94.8%

Procedure

Condensation between 1-(3-aminopropyl) piperidine (427 mg) and 2,4-dibenzoyloxybenzoic acid (1.0 g) is carried out in the same manner as in Example 7, i) to yield 1-[3-(2,4-dibenzyloxybenzoyl)aminopropyl]piperidine (1.2 g).

Sources & evidence

ORD record
ord-6d2e1cdd82e548308902eff563666f8b
Source dataset
uspto-grants-1991_02
Patent number
US04990511

Reaction notes

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