Acetic Acid → HCID 67928038, compound

Participants

Reaction Steps

To a solution (20 ml) of 1-(2,4-dibenzyloxyphenylacetyl)amino-5-(3-benzyloxycarbonylaminopropionyl)aminopentane (440 mg) in ethanol are added 10 % palladiumcarbon (70 mg) and acetic acid (0.01 ml) and catalytic reduction is conducted in a hydrogen stream at room temperature under atmospheric pressure. After four hours, the catalyst is removed by filtration and the filtrate is concentrated under reduced pressure. To the glass-like product obtained is added ether to digest into powder. The resulting product is filtered and dried to yield 1-(2,4-dihydroxyphenylacetyl)amino-5-(3-aminopropionyl)aminopentane acetate (209 mg).

Provenance & Evidence