HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 15093148, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 70083343 | HCID 70083343 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 15093148 | HCID 15093148 | 97% |
Reaction Steps
The above hydrochloride, 4.0 g (0.008 mole) in water was treated with ammonium hydroxide and the aqueous suspension was extracted with methylene chloride. The methylene chloride solutions were dried (MgSO4) and removal of the solvent gave 3.6 g (97%) of rac.-cis-6-(acetyloxy)-6,7-dihydro-7(4-methoxyphenyl)-4-[2-(dimethylamino)-ethyl]-3-phenyl-1 , 4-thiazepin-5(4H)-one. Analytical sample was recrystallized from ether, mp 115°-116°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04992432 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-80af12559e9e40b690d34b7d6510e0c4 |
| Source note | uspto-grants-1991_02 |