Pyrimethanil → 116389-21-0

HRID 981480Notes

Reaction equation

HRID 981480 reaction equation
[NH:1]([C:8]1[N:13]=[C:12]([CH3:14])[CH:11]=[C:10]([CH3:15])[N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:16]([O-])=[O:17].[Na+]>C(O)(=O)C.O>[CH3:14][C:12]1[CH:11]=[C:10]([CH3:15])[N:9]=[C:8]([N:1]([N:16]=[O:17])[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[N:13]=1

Participants

5

Reactant 2

HCID 91650PyrimethanilHCID 23668193Sodium Nitrite

Product 1

HCID 14327551116389-21-0Yield 74.2%

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent2×

Procedure

To a solution of 2.0 g of 2-anilino-4,6-dimethylpyrimidine in 15 ml of acetic acid was added dropwise a solution of 1.4 g of sodium nitrite in 10 ml of water. After 30 minute's stirring, 50 ml of water was added to the mixture. The resulting crystals were collected by filtration and dried. Recrystallization from ethanol afforded 1.7 g (yield: 74%) of 4,6-dimethyl-2-(N-nitrosoanilino)pyrimidine having a melting point of 117°-121° C.

Workup

  1. filtrationThe resulting crystals were collected by filtration
  2. customdried
  3. customRecrystallization from ethanol

Sources & evidence

ORD record
ord-1016a16bfafb491b90d9761e9c7e350e
Source dataset
uspto-grants-1991_02
Patent number
US04992438

Reaction notes

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