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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 981510Generated: October 31, 2026

1-Ethyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 18643684, compound

https://huagongshe.com/reaction/981510

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 800521—
ReactantHCID 12446101HCID 12446101—
SolventPyridineHCID 1049—
ProductHCID 18643684HCID 18643684—

Reaction Steps

A mixture of 1-ethyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid and cis 1,2-diamino cyclopropane [Synthetic Communications, 11(6), 493-495 (1981)] in pyridine is reacted as described in Example 1 giving the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04992449
Source datasetuspto-grants-1991_02
ORD IDord-c972d5ec153a411ab098aaaa2538578c
Source noteuspto-grants-1991_02