Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 981579Generated: October 30, 2026

Malonic Acid → 3,5-Dichlorocinnamic acid

https://huagongshe.com/reaction/981579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalonic AcidHCID 867—
ReactantPiperidineHCID 8082—
Reactant3,5-DichlorobenzaldehydeHCID 35746—
SolventPyridineHCID 1049—
Product3,5-Dichlorocinnamic acidHCID 17650469%

Reaction Steps

Reaction of 3,5-dichlorobenzaldehyde (26.9 g, 0.154 mole), malonic acid (24.1 g, 0.232 mole), pyridine (8 ml) and piperidine (0.4 ml) substantially as above yielded 22.9 g (69%) of 3,5-dichlorocinnamic acid as white needles: mp 169-170° (ethanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04992459
Source datasetuspto-grants-1991_02
ORD IDord-282a6ad4e33d492eb9305ceb564bdb6d
Source noteuspto-grants-1991_02