3,5-Dichlorocinnamic acid → 3-(3,5-Dichlorophenyl)propionic acid

HRID 981580Notes

Reaction equation

HRID 981580 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]=[C:11]([Cl:13])[CH:12]=1)[CH:5]=[CH:6][C:7]([OH:9])=[O:8]>[Pd]>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:5][CH2:6][C:7]([OH:9])=[O:8])[CH:10]=[C:11]([Cl:13])[CH:12]=1

Participants

3

Reactant 1

HCID 1765043,5-Dichlorocinnamic acid

Product 1

HCID 8193053-(3,5-Dichlorophenyl)propionic acidYield 99%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Reaction of 3,5-dichlorocinnamic acid (22.9 g, 0.106 mol) and 3 g palladium/carbon substantially as above yielded 23 g (99%) of 3-(3',5'-dichlorophenyl)propanoic acid as an oil.

Sources & evidence

ORD record
ord-40230b36111447c9a34db76dcd9c9bde
Source dataset
uspto-grants-1991_02
Patent number
US04992459

Reaction notes

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