Diethyl Ether → HCID 67947580, compound

Participants

Reaction Steps

2 g of 6-(7-carboxy-3-methyl-2,6-octadienyl)-2,3,4-trimethoxy-5-methylphenol as prepared in Example 1 was dissolved in 20 ml of ethyl acetate and 5 g of ferric chloride hexahydrate was added thereto. The reaction mixture was stirred at room temperature for 30 min. After adding 100 ml of ether, it was washed with water, dried over anhydrous magnesium sulfate and concentrated. The concentrate was purified by means of silica gel chromatography with the use of ethyl acetate/benzene as the eluent to give 1.8 g of the title compound as an orange oil.

Provenance & Evidence