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HRID981776

反应详情

EQUATION

反应方程式

HRID 981776 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@]4(C)CC[C@@H]1[C@]32OO4
HCID9838675

未命名化合物

2 次

结构：C=C(C(=O)O)[C@@H]1CC[C@@H](C)[C@@H]2CCC(C)=C[C@@H]21
HCID10922465

未命名化合物

2 次

PRODUCTS

生成物

2
结构：C=C(C(=O)O)[C@@H]1CC[C@@H](C)[C@@H]2CCC(C)=C[C@@H]21
HCID10922465

未命名化合物

结构：C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@]4(C)CC[C@@H]1C32O4
HCID45038803

未命名化合物

PROCEDURE

实验过程

Because there is far more artemisinic acid (Compound 1) than artemisinin (Compound 3) in Artemisia annua, the conversion of the former to the latter has received a great deal of attention. Prior synthetic conversion of 1 to 3 required a greater number of steps, produced a yield of approximately 7% and required the use of column chromatography for purification of the resulting artemisinin. Other attempts to simplify the process resulted in conversion of artemisinic acid into desoxyartemisinin, but did not . result in conversion to artemisinin.

WORKUP

后处理

  1. customproduced a yield of approximately 7%
  2. customfor purification of the resulting artemisinin