Dodecanoyl chloride → HCID 20070874, compound

Participants

Reaction Steps

Using the same reaction conditions as those of Example 4, 3-(aminomethyl)thiophene hydrochloride (4 mmol), triethylamine (4.4 mmol) and dodecanoyl chloride (4.0 mmol) were reacted to give N-(3-thienylmethyl)dodecanamide (1.1 g, 92%) M.p. 83°-84° C. (Found: C, 68.9; H, 10.2; N, 4.8; S, 10.8. Calculated for C17H29NOS: C, 69.1; H, 9.8; N, 4.7; S, 10.9%); EI m/e Intensity (%): 295 (18, M+), 97 (46, C4H3S.CH2+); δH(CDCl3) 7.01-7.30 (3H, m), 5.80 (1H, br,s), 4.46 (2H, d), 2.20 (2H, t), 1.80 (2H, m), 1.25 (16H, m), 0.87 (3H, t);

Provenance & Evidence