Sodium Hydroxide → HCID 67591107, compound

Participants

Reaction Steps

300 mg of ethyl p-[(E)-2-(6,7,8,9-tetrahydro-5H-benzocyclohepten -2-yl)propenyl]benzoate are treated in 20 ml of ethanol with 2 ml of 2.5M sodium hydroxide solution. The mixture is stirred at room temperature for 48 hours, diluted with water and extracted with diethyl ether. The aqueous phase is acidified, extracted with ether. The ethereal phase is washed with water, dried and evaporated. There are obtained 200 mg of p-[(E)-2-(6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)propenyl]benzoic acid of m.p. 198°.

Provenance & Evidence