HCID 54054685, compound → HCID 53687673, compound

HRID 981848Notes

Reaction equation

HRID 981848 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[CH:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15])=[CH:5][CH:4]=1.[CH3:16][O:17][C:18](=[O:38])[CH2:19][CH2:20][C:21]1[CH:26]=[C:25]([C:27](=[O:36])[C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([C:34]#[N:35])[CH:29]=2)[CH:24]=[CH:23][C:22]=1O>>[CH3:16][O:17][C:18](=[O:38])[CH2:19][CH2:20][C:21]1[CH:26]=[C:25]([C:27](=[O:36])[C:28]2[CH:33]=[CH:32][CH:31]=[C:30]([C:34]#[N:35])[CH:29]=2)[CH:24]=[CH:23][C:22]=1[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH:10]=[CH:9][C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 54054685HCID 54054685, compoundHCID 54092419HCID 54092419, compound

Product 1

HCID 53687673HCID 53687673, compoundYield 34.1%

Procedure

Following the general procedure of Example 92B, 1.63 g of 6-(4-methoxyphenyl)-5-hexenyl alcohol were converted to its mesyl ester and reacted with 2.45 g of 5-(3-cyanobenzoyl)-2-hydroxybenzenepropanoic acid methyl ester to provide 1.34 g of 5-(3-cyanobenzoyl)-2{[6-(4-methoxyphenyl)-5-hexenyl]oxy]benzenepropanoic acid methyl ester, m.p. 65°-67° C.

Sources & evidence

ORD record
ord-e2af64e4acc04cc1abc1537a43cd4e36
Source dataset
uspto-grants-1991_02
Patent number
US04992576

Reaction notes

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