HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 3-Ethyl-1-(t-butyldimethylsilyl)-4-vinyl-2-azetidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | HCID 12769229 | HCID 12769229 | — |
| Reactant | 8-Oxo-2,2-dimethyl-7alpha-isopropyl-3-oxa-1-azabicyclo[4.2.0]octane | HCID 13051144 | — |
| Reactant | 1-(t-Butyldimethylsilyl)-4-vinyl-2-azetidinone | HCID 14068169 | — |
| Product | 3-Ethyl-1-(t-butyldimethylsilyl)-4-vinyl-2-azetidinone | HCID 15137369 | — |
Reaction Steps
Following the procedure for the preparation of 8-oxo-2,2-dimethyl-7α-isopropyl-3-oxa-1-azabicyclo[4.2.0]octane (Example 4a, above), except that an equivalent amount of 1-(t-butyl-dimethylsilyl)-4-vinyl-2-azetidinone is substituted for the 8-oxo-2,2-dimethyl-3-oxa-1-azabicyclo [4.2.0]octane of Example 4a and using ethyl iodide instead of isopropyl iodide, the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04992542 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-59f01bbd4ab24fb382e9b996ab309c98 |
| Source note | uspto-grants-1991_02 |