2-Bromopyridine → 2-[(3-Nitro-2,4-dimethylphenyl)-amino]-pyridine

Participants

Reaction Conditions

Reaction Steps

3.3 g of 3-Nitro-2,4-dimethylaniline and 3.2 g of 2-bromo-pyridine are mixed and the resulting mixture heated for 8 hours to 170° C. After cooling to 20° C., the greasy mass formed was dissolved in water and the solution pH then raised by addition of sodium carbonate. The resulting precipitate was recrystallized from ethanol. 2 g of the product melting at 178° to 179° C. were obtained. Another 2.1 g of the substance were obtained from the aqueous phase by concentration.

Provenance & Evidence