Acetic Anhydride → HCID 178479926, compound

Participants

Reaction Steps

20 ml of acetic anhydride was added to 1.0 g of Compound b obtained in Reference Example 2, followed by refluxing for 5 hours. After the reaction solution was concentrated under reduced pressure, methanol was added to the residues. The solution was adjusted to a pH of 9 to 10 with sodium methoxide. The precipitate was collected by filtration and washed with methanol, to afford 0.63 g of Compound c.

Provenance & Evidence