HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde oxime hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde | HCID 15158179 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde oxime hydrochloride | HCID 86743918 | 45.5% |
Reaction Steps
A mixture of 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde (0.5 g) and hydroxylamine hydrochloride (0.17 g) in ethanol (5 ml) was refluxed for 1.5 hours and evaporated in vacuo. The residue was triturated with ethyl acetate and recrystallized from a mixture of ethanol and ethyl acetate to give 2-phenylpyrazolo[1,5-a]pyridine-3-carbaldehyde oxime hydrochloride (0.28 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04994453 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-9adf7bc89ce3430daf5f3be9797cfac1 |
| Source note | uspto-grants-1991_02 |