3,4,6-Trifluoro-5-hydroxyphthalic acid → 2,4,5-Trifluoro-3-hydroxybenzoic Acid

HRID 982194ノート

反応式

HRID 982194 の反応式
[F:1][C:2]1[C:10]([OH:11])=[C:9]([F:12])[C:8]([F:13])=[C:4](C(O)=O)[C:3]=1[C:14]([OH:16])=[O:15]>O>[F:1][C:2]1[C:10]([OH:11])=[C:9]([F:12])[C:8]([F:13])=[CH:4][C:3]=1[C:14]([OH:16])=[O:15]

参加物

3

反応物 1

HCID 101985873,4,6-Trifluoro-5-hydroxyphthalic acid

生成物 1

HCID 27342702,4,5-Trifluoro-3-hydroxybenzoic Acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Japanese Patent Application 86/290399 as abstracted in Chem. Abstracts (CA109 (19) 170038e), discloses that 3,5,6-trifluoro-4-hydroxyphthalic acid may be decarboxylated by heating the compound for three hours, in water, under nitrogen atmosphere, at 140° C. (in a sealed tube) to yield 2,4,5-trifluoro-3-hydroxybenzoic acid.

後処理

  1. temperatureby heating the compound for three hours

出典と根拠

ORDレコード
ord-877a3e9244a747f69803f38b4f9a5dd2
出典データセット
uspto-grants-1991_02
特許番号
US04994606

反応ノート

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