Sodium hydride → HCID 14650679, compound

Participants

Reaction Steps

Working in a manner similar to that described in Example 16, but starting with an oily suspension (50% by weight; 0.31 g) of sodium hydride, (5RS, 6SR)-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazin-5-ol (1.52 g) and 2-fluorophenyl isocyanate (0.9 g), and after recrystallization in diisopropyl ether, (5RS, 6SR)-5-(2-fluorophenylcarbamoyloxy)-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine (0.67 g), m.p. 98° C., is obtained.

Provenance & Evidence