3-Furoic acid → HCID 14650588, compound

HRID 982261Notes

Reaction equation

HRID 982261 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:17]=CC=1)[C:5]([NH:7][CH2:8]/[CH:9]=[CH:10]/[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:6].[O:20]1C=CC(C(O)=O)=C1.C(N)/C=C/C1C=CC=CC=1>>[CH2:8]([NH:7][C:5]([C:4]1[CH:3]=[CH:2][O:20][CH:17]=1)=[O:6])/[CH:9]=[CH:10]/[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 3

HCID 102683-Furoic acidHCID 6008559cinnamylamineHCID 14650584HCID 14650584, compound

Product 1

HCID 14650588HCID 14650588, compound

Procedure

(E)-N-Cinnamyl-3-furancarboxamide may be obtained in the following manner: working as in Example 21 for the preparation of (E)-3-chloro-N-cinnamylbenzamide, but starting with 3-furancarboxylic acid (4 g) and (E)-cinnamylamine (4 g), and after recrystallization in isopropyl ether, (E)-N-cinnamyl-3-furancarboxamide (3.9 g), m.p. 115° C. is obtained.

Workup

  1. customafter recrystallization in isopropyl ether

Sources & evidence

ORD record
ord-de664ec77e164d168dac802e584883f8
Source dataset
uspto-grants-1991_02
Patent number
US04994569

Reaction notes

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