2-Naphthoic acid → HCID 20069302, compound

HRID 982286Notes

Reaction equation

HRID 982286 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][CH:19]=1)[C:5]([NH:7][CH2:8]/[CH:9]=[CH:10]/[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:6].[CH2:20](N)[CH:21]=[CH:22][C:23]1C=CC=CC=1.C1C2C(=CC=CC=2)C=CC=1C(O)=O>>[CH2:8]([NH:7][C:5]([C:4]1[CH:17]=[CH:18][C:19]2[C:2](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:3]=1)=[O:6])/[CH:9]=[CH:10]/[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 3

HCID 71232-Naphthoic acidHCID 203693-Phenylprop-2-en-1-amineHCID 14650584HCID 14650584, compound

Product 1

HCID 20069302HCID 20069302, compound

Procedure

(E)-N-Cinnamyl-2-naphthalenecarboxamide may be obtained in the following manner: working in a manner similar to that described in Example 21 for the preparation of (E)-3-chloro-N-cinnamylbenzamide, starting with cinnamylamine (5.3 g) and 2-naphthoic acid (7.6 g), and after recrystallization in ethyl acetate, (E)-N-cinnamyl-2-naphthalenecarboxamide (4.3 g) is obtained.

Workup

  1. customafter recrystallization in ethyl acetate

Sources & evidence

ORD record
ord-86ff9564c95d4b63aad246030923c8f0
Source dataset
uspto-grants-1991_02
Patent number
US04994569

Reaction notes

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