HCID 20067563, compound → HCID 20067590, compound

Participants

Reaction Steps

To a solution of 7H-benzo[4,5]cyclohepta[1,2-a]naphthalen-7-one (1.75 g, prepared by the method of Bergmann et al, J. Org. Chem., 1963, 28, 3341) in dry tetrahydrofuran (40 ml) at 0° C. under nitrogen was added a solution of methyl lithium in diethyl ether (8 ml of 1.4M). After 90 minutes at 0° C. the reaction was quenched by the dropwise addition of water (20 ml) and the reaction mixture extracted into diethyl ether (2×75ml). dried (Na2SO4), filtered and the solvents removed under reduced pressure to give a light brown oil (1.9 g).

Provenance & Evidence