Tetronic acid → HCID 54244004, compound

Participants

Reaction Steps

As before, 0.571 gm of tetronic acid (FW=100, 5.7 mmole) was reacted with 2.2 equiv. or 1.96 gm of 5-carboxy-2-thiophenecarboxaldehyde with 6 mL of THF and 10.5 mL of conc. HC1 and applied heat. A greenish precipitate formed immediately. Stirring was continued for 10 minutes. Workup and recrystallization from methanol gave 0.91 gm (67%) of the product having a M. p. of approximately 255°-268° C. and a molecular formula of C10H6O5S: calculated %C 50.42; %H 2.54; found %c 50.22; %H 2.75.

Provenance & Evidence