3-Methyl-2-thiophenecarboxaldehyde → HCID 53965120, compound

Participants

Reaction Steps

1.00 gm of tetronic acid (FW=100, 10mmole) was added to a stirring solution of 3.78 gm of 3-methyl-2-thiophenecarboxaldehyde (FW=126, 30 mmole) together with 1 mL conc. Hc1. The mixture was stirred for 40 minutes after which all had solidified. The residue was dissolved in CHCl3 and washed with water, dried with HgSO4, filtered and put through a silica plug with CHCl3. The yellow crystals had a melting point of 164°-166° C. (lit. 164-165). The yield was 42%. All other spectral data corresponded with the published ones. C10H8O3S: %C 57.69; %H 3.87; found %C 57.81; %H 3.82. NMR results: 1HNMR (d6DMSO(H2 0)/TMS) δ 2.56 (3H, s); 4.71 (2H, d, 7 Hz); 7.28 (1H, m); 8.01 (1H, m); 8.27 (1H, m).

Provenance & Evidence