HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dibromoethane → 1,2-Diphenyl-1-[4-(2-bromoethoxy)phenyl]-1-buten-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dibromoethane | HCID 11201 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Z-4-(4-hydroxy-1,2-diphenyl-but-1-enyl)-phenol | HCID 13298065 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | 1,2-Diphenyl-1-[4-(2-bromoethoxy)phenyl]-1-buten-4-ol | HCID 54464616 | — |
Reaction Steps
A mixture containing 31.6 g of (Z)-1,2-diphenyl-1-(4-hydroxyphenyl)-1-buten-4-ol, 93.9 g of dibromoethane, 20.7 g of anhydrous potassium carbonate and 250 ml of methyl ethyl ketone is refluxed for 24 h. The inorganic salts are removed by filtration followed by evaporating the solvent and recrystallizing from methanol. The yield is 17.3 g (41%) and m.p. 133°-7° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04996225 |
| Source dataset | uspto-grants-1991_02 |
| ORD ID | ord-779fa5d296e14f008aece5d991d133c1 |
| Source note | uspto-grants-1991_02 |