Methanesulfonic Acid → HCID 15718098, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.5 g of phosphorous pentoxide and 25 ml of methanesulfonic acid were stirred together under a nitrogen atmosphere overnight. To this mixture were added 2.3 g of 2,4'-dicarboxy-5-methoxybiphenyl. The reaction mixture was stirred at room temperature for six hours with the addition of methanesulfonic acid to keep the mixture sufficient for stirring. The mixture was then warmed to 40° C. for one hour, cooled, and poured into ice water. The resulting yellow-green precipitate was recovered by filteration, washed with water, and dried to provide 1.6 g of the desired subtitle intermediate.

Provenance & Evidence