HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 1-pyridyl-3-phenyl-5-aminopyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Benzoylacetonitrile | HCID 64799 | — |
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 1-pyridyl-3-phenyl-5-aminopyrazole | HCID 12288136 | 80.5% |
Reaction Steps
To a solution of 1.09 g 2-hydrazinopyridine in 10 ml 5N hydrochloric acid was added 1.45 g benzoylacetonitrile (from Example 2) under stirring. The mixture was refluxed for 3 hrs. After cooling, the solution was neutralized with Na2CO3. The yellow precipitate was filtrated, washed with H2O, and dried to get 1.9 g 1-pyridyl-3-phenyl-5-aminopyrazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06861162B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-7c96b55dfb784c90af3c147605115390 |
| Source note | uspto-grants-2005_03 |