反应详情

1.78 g N,N-diethyl-p-nitrosoaniline and 2.67 g 3-phenyl-1-(2-pyridyl)-5-aminopyrazole were refluxed for 2 hrs in acetic acid. The mixture was concentrated to half volume. Water was added to get a precipitate, then filtered. The solid was purified by chromatograph column on silica gel. After removing the solvent, 1.3 g pure 7-diethylamino-3-phenyl-1-(2-pyridyl)-1H-pyrazolo[3,4-b]quinoxaline (DEPPPQ) was obtained as brown-red solid.

1. concentrationThe mixture was concentrated to half volume
2. additionWater was added
3. customto get a precipitate
4. filtrationfiltered
5. customThe solid was purified by chromatograph column on silica gel
6. customAfter removing the solvent