Pentaerythritol → p-Toluenesulfonic acid

Participants

Reaction Steps

A mixture of 0.2 g (0.54 mmol) of compound 9, 0.2 g (1.7 mmol) of 1,1,1-tris(hydroxymethyl)ethanol and 0.13 g (0.7 mmol) of p-TsOH.H2O in 30 mL of toluene was refluxed for 16 h, cooled to room temperature and filtered. The white solid product was isolated as a p-toluene sulfonic acid salt (0.19 g) (mass spec. MH+=470. Mpt.=223-226.5° C.).

Provenance & Evidence