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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982734Generated: October 26, 2026

3-Chloroacetylpyridine → (1S)-2-(methylamino)-1-pyridin-3-ylethanol

https://huagongshe.com/reaction/982734

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-ChloroacetylpyridineHCID 416252—
Reactant(R)-2-(methylamino)-1-pyridin-2-ylethanolHCID 10149007—
Product(1S)-2-(methylamino)-1-pyridin-3-ylethanolHCID 10171254—

Reaction Steps

As described for the preparation of (1R)-2-(methylamino)-1-pyridin-2-ylethanol (Preparations 27-28), 3-chloroacetylpyridine (Chem. Ber. 1951, 84, 147-149) is converted to the title compound, isolated as a pale yellow amorphous solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861438B2
Source datasetuspto-grants-2005_03
ORD IDord-67e4a5371e76474ab01f2d2f05bc0b35
Source noteuspto-grants-2005_03