HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanolamine → 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(2-hydroxyethyl)aminomethyl-2H-pyridazin-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanolamine | HCID 700 | — |
| Edukt | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-methylaminomethyl-2H-pyridazin-3-one | HCID 21991518 | — |
| Edukt | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-meth anesulfonyloxymethyl-2H-pyridazin-3-one | HCID 21991618 | — |
| Produkt | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(2-hydroxyethyl)aminomethyl-2H-pyridazin-3-one | HCID 21991705 | 72,1% |
Reaktionsschritte
Following the procedure of Example 9 (4), 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-methane-sulfonyloxymethyl-2H-pyridazin-3-one and 2-aminoethanol were reacted to yield the title compound as a yellow oil (yield: 72.1%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06861428B2 |
| Quelldatensatz | uspto-grants-2005_03 |
| ORD ID | ord-34e5e80cea864f68b594b1ac0b81881f |
| Quellennotiz | uspto-grants-2005_03 |