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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982770Generated: November 1, 2026

1-Methylpiperazine → 6-(4-biphenylyl)-2-isobutyl-4-(4-methyl-1-piperazinyl)methyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/982770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant6-(4-biphenylyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-oneHCID 21991575—
Product6-(4-biphenylyl)-2-isobutyl-4-(4-methyl-1-piperazinyl)methyl-2H-pyridazin-3-oneHCID 2199169268.2%

Reaction Steps

Following the procedure of Example 1(10), 6-(4-biphenylyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-one and 1-methylpiperazine were reacted to yield the title compound as a yellow oil (yield: 68.2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861428B2
Source datasetuspto-grants-2005_03
ORD IDord-4d9331765c144088b656cf08c8d4eb63
Source noteuspto-grants-2005_03