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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982774Generated: October 31, 2026

Diethylamine → 4-diethylaminomethyl-6-(4-fluoro-3-methylphenyl)-2-isobutyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/982774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylamineHCID 8021—
Reactant6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-oneHCID 21991457—
Reactant6-(4-fluoro-3-methylphenyl)-2-isobutyl-4-methoxycarbonyl-2H-pyridazin-3-oneHCID 21991533—
Product4-diethylaminomethyl-6-(4-fluoro-3-methylphenyl)-2-isobutyl-2H-pyridazin-3-oneHCID 21991594—

Reaction Steps

Following the procedure of Example 9 (4), 6-(4-fluoro-3-methylphenyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-one and diethylamine were reacted to yield the title compound as a slightly yellow oil (yield: 94.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861428B2
Source datasetuspto-grants-2005_03
ORD IDord-683d54e8dd6545eebdb59cf73078e581
Source noteuspto-grants-2005_03