Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 982786Generated: October 31, 2026

1-Methylpiperazine → 2-cyclopropylmethyl-4-(4-methyl-1-piperazinyl)methyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one

https://huagongshe.com/reaction/982786

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant2-cyclopropylmethyl-4-methanesulfonyloxymethyl-6-[4-(methyl thio)phenyl]-2H-pyridazin-3-oneHCID 21991557—
Product2-cyclopropylmethyl-4-(4-methyl-1-piperazinyl)methyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-oneHCID 1027137685.7%

Reaction Steps

Following the procedure of Example 1(10), 2-cyclopropylmethyl-4-methanesulfonyloxymethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one and 1-methyl-piperazine were reacted to yield the title compound as a yellow oil (yield: 85.7%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861428B2
Source datasetuspto-grants-2005_03
ORD IDord-ddac44eb05914b2d9fc14102ab24aca2
Source noteuspto-grants-2005_03