HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl chloride → 2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl chloride | HCID 9602 | — |
| Reactant | 6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991432 | — |
| Product | 2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991566 | 86.6% |
Reaction Steps
Following the procedure of Example 1(6), 6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and 4-fluorobenzyl chloride were reacted to yield the title compound as a slightly-yellow crystalline powder (yield: 86.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06861428B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-b04e522af1ef4e128dac5f23df05ed9d |
| Source note | uspto-grants-2005_03 |