HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Chlorophenyl)ethyl methanesulfonate → 2-[2-(2-chlorophenyl)ethyl]-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Chlorophenyl)ethyl methanesulfonate | HCID 21888087 | — |
| Reactant | 6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991459 | — |
| Product | 2-[2-(2-chlorophenyl)ethyl]-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 22562248 | 59.8% |
Reaction Steps
Following the procedure of Example 1(6), 6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and 2-(2-chlorophenyl)ethanol methanesulfonate were reacted to yield the title compound as a pale yellow solid (yield: 59.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06861428B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-11cf328b860b422bb54e1a25c3c40802 |
| Source note | uspto-grants-2005_03 |