HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cysteamine → 4-Hydroxy-6-methyl-3-[2-(2,3,4-trimethoxy-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl]-5,6-dihydro-pyran-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cysteamine | HCID 6058 | — |
| Reactant | 2-Aminothiophenol | HCID 8713 | — |
| Reactant | 4-Hydroxy-3-[(E)-3-(2-methoxy-4-methylsulfanyl-phenyl)-acryloyl]-6-methyl-pyran-2-one | HCID 135621892 | — |
| Reactant | HCID 178490174 | HCID 178490174 | — |
| Product | 4-Hydroxy-6-methyl-3-[2-(2,3,4-trimethoxy-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl]-5,6-dihydro-pyran-2-one | HCID 135450044 | — |
Reaction Steps
Proceeding as in Example 2, but 4-hydroxy-6-methyl-3-[(E)-3-(2,3,4-trimethoxy-phenyl)-acryloyl]-5,6-dihydro-pyran-2-one substituted for 4-hydroxy-3-[(E)-3-(2-methoxy-4-methylsulfanyl-phenyl)-acryloyl]-6-methyl-pyran-2-one and 2-amino-benzenethiol for 2-aminoethanethiol, provided 4-hydroxy-6-methyl-3-[2-(2,3,4-trimethoxy-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepin-4-yl]-5,6-dihydro-pyran-2-one (Compound 56); MS M+ 456.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06861419B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-7bbf327077f141caa227e3fe0ff49324 |
| Source note | uspto-grants-2005_03 |