L-Alanine → N-(3-chlorophenylacetyl)alanine
Reaction equation
[NH2:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3].[Cl:7][C:8]1[CH:9]=[C:10]([CH2:14][C:15](O)=[O:16])[CH:11]=[CH:12][CH:13]=1>>[Cl:7][C:8]1[CH:9]=[C:10]([CH2:14][C:15]([NH:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3])=[O:16])[CH:11]=[CH:12][CH:13]=1Participants
3
Procedure
The title compound was prepared using L-alanine (Nova Biochem) and 3-chlorophenyl acetic acid (Aldrich) by following General Procedures F′ or G′, followed by hydrolysis using General Procedure D′.
Workup
- customfollowed by hydrolysis
Sources & evidence
- ORD record
- ord-01af0e2486364b1dbae642c75b5156e2
- Source dataset
- uspto-grants-2005_03
- Patent number
- US06861558B2
Reaction notes
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