HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Tolylacetic acid | HCID 248474 | — |
| Reactant | 2-methylpropyl (2S)-2-aminopropanoate | HCID 13743556 | — |
| Product | N-[(4-methylphenyl)acetyl]alanine iso-butyl ester | HCID 53936136 | — |
Reaction Steps
Following General Procedure I′ above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06861558B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-159695c25f024643951ceb6ef0d90d0e |
| Source note | uspto-grants-2005_03 |