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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983279Generated: October 30, 2026

HCID 10867190, compound → HCID 10202141, compound

https://huagongshe.com/reaction/983279

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10867190HCID 10867190—
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
ProductHCID 10202141HCID 10202141—

Reaction Steps

Following General Procedure A and using N-(3,5-difluorophenylacetyl)-L-alanine (from Example B2 above) and methyl (S)-2-amino-4-phenylbutanoate (prepared from (+)-α-amino-4-phenylbutyric acid (Bachem) using General Procedure AG), the title compound was prepared as a solid (mp=147-149.5° C.). The reaction was monitored by tlc (Rf=0.32 in 50% EtOAc/hexanes) and the product was purified by flash chromotography using EtOAc/hexanes as the eluent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861558B2
Source datasetuspto-grants-2005_03
ORD IDord-520a6027a7d04c8c9346dc96a16aad3f
Source noteuspto-grants-2005_03