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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983305Generated: October 30, 2026

Methyl 2-amino-2-methylpropanoate → HCID 22894870, compound

https://huagongshe.com/reaction/983305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-2-methylpropanoateHCID 4186341—
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
SolventChloroform methanolHCID 21584188—
ProductHCID 22894870HCID 22894870—

Reaction Steps

Following General Procedure C and using N-(3,5-difluorophenylacetyl)-L-alanine (from Example B2 above) and methyl 2-aminoisobutyrate (prepared from 2-aminoisobutyric acid (Aldrich) using General Procedure H), the title compound was prepared as a solid. The reaction was monitored by tlc (Rf=0.25 in CHCl3/MeOH 95:5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06861558B2
Source datasetuspto-grants-2005_03
ORD IDord-96eafae322d946a3a9260d5ce220057a
Source noteuspto-grants-2005_03