反应详情

A solution of 1.13 g of 1-methyl-2-[(2-nitrophenoxy)methyl]-1H-imidazole in 70 ml of methanol with 0.14 g of palladium on charcoal 10% was hydrogenated at 50 psi for 6 hours at room temperature. The catalyst was then separated by filtration and the solvent evaporated. The residue was finally purified by chromatography on a silica gel column (eluent: chloroform-methanol 48/2) giving rise 0.856 g of the title compound as a red oil.

1. customThe catalyst was then separated by filtration
2. customthe solvent evaporated
3. customThe residue was finally purified by chromatography on a silica gel column (eluent: chloroform-methanol 48/2)