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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983379Generated: October 29, 2026

3,4,5-Trimethoxyaniline → 2,3,4-Trimethoxycyclohexylamine

https://huagongshe.com/reaction/983379

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5-TrimethoxyanilineHCID 32285—
Reactant5-Aminoisophthalic acidHCID 66833—
Product2,3,4-TrimethoxycyclohexylamineHCID 22559933—

Reaction Steps

3,4,5-trimethoxyaniline was hydrogenated via the procedure given for 3,5-dicarboxy-aniline to provide 2,3,4-trimethoxycyclohexylamine which was coupled to the C-terminal valine in the standard way.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06864240B1
Source datasetuspto-grants-2005_03
ORD IDord-a3a9e9d927f14451a6335b8df3b58b56
Source noteuspto-grants-2005_03