3-Bromoaniline → HCID 22560110, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of 2-[3-(4-chloro-[1,3,5]triazin-2-ylamino)-phenyl]acetamide (36.6 mg, 0.1388 mmol) in IpOH (1 ml) were added DIEA (27 μl, 0.1527 mmol) and 3-bromoaniline (26.3 mg, 0.1527 mmol). The mix was heated at 100-120° C. for 18 h. The solution was cooled to RT and sonicated. The precipitate was filtered and dried under reduced pressure, giving 2-{3-[4-(3-bromophenylamino)-[1,3,5]triazin-2-ylamino]-phenyl}acetamide.

Provenance & Evidence