Potassium Carbonate → HCID 22560089, compound

Participants

Reaction Conditions

Reaction Steps

(4-Chloro-[1,3,5]triazin-2-yl)-(3-[1,2,3]triazol-1-ylmethyl-phenyl)-amine (552.7 mg, 1.921 mmol) is combined with 2-chlorobenzimidazole (381 mg, 2.497 mmol) and K2CO3 (372 mg, 2.689 mmol) in AcCN (10 ml) and heated at 65-75° C. for 2 to 20 h. The reaction mix is cooled to RT and diluted with MeOH and CH2Cl2. The inorganic salts are filtered off and the organic solution is concentrated under reduced pressure. The crude is treated with AcCN (5-8 ml), forming a precipitate. The precipitate is filtered and dried, giving [4-(2-chloro-benzoimidazol-1-yl)-[1,3,5]triazin-2-yl]-(3-[1,2,3]triazol-1-ylmethyl-phenyl)-amine.

Provenance & Evidence