HCID 22561366, compound → HCID 22269445, compound

HRID 983752Notes

Reaction equation

HRID 983752 reaction equation
[CH3:1][C:2]1[CH:30]=[CH:29][C:5]([C:6]([C:8]2[CH:16]=[C:15]([C:17](=O)[C:18]3[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][CH:19]=3)[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]=2[C:26]([OH:28])=[O:27])=O)=[CH:4][CH:3]=1.[H][H]>[Pd].C(O)(=O)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][C:8]2[CH:16]=[C:15]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([CH3:24])=[CH:20][CH:19]=3)[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]=2[C:26]([OH:28])=[O:27])=[CH:29][CH:30]=1

Participants

5

Reactant 2

HCID 22561366HCID 22561366, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 22269445HCID 22269445, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

A mixture of 21.1 grams of 4,6-bis(4-methylbenzoyl)isophthalic acid, 350 mL of acetic acid, and 2.10 grams of 5% palladium on carbon (as a catalyst) was heated to 65° C. for 17 hours in an atmosphere of hydrogen at 270 kPa. The resulting mixture was filtered through Celite™ diatomaceous earth filter agent to remove the catalyst. The filtrate was concentrated in vacuo to give 4,6-bis(4-methylbenzyl)isophthalic acid.

Workup

  1. filtrationThe resulting mixture was filtered through Celite™ diatomaceous earth
  2. filtrationfilter agent
  3. customto remove the catalyst
  4. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-8b20d8a3588847598aafb79c19749a54
Source dataset
uspto-grants-2005_03
Patent number
US06864396B2

Reaction notes

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