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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983836Generated: October 25, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine

https://huagongshe.com/reaction/983836

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
Reactant3,5-Dimethoxy-benzamidineHCID 3627849—
Product5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-AmineHCID 448436—

Reaction Steps

The title compound, MS: m/e=405.4 (M+H+), was prepared from 3,5-dimethoxy-benzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-f0136afbb85f4cc7a6521787f39f0efe
Source noteuspto-grants-2005_03