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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983840Generated: October 27, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-(1H-indol-2-yl)-pyrimidin-4-ylamine

https://huagongshe.com/reaction/983840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
Reactant1H-Indole-2-carboximidamideHCID 135677716—
Product5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-(1H-indol-2-yl)-pyrimidin-4-ylamineHCID 10237409—

Reaction Steps

The title compound, MS: m/e=383.9 (M+H+), was prepared from 1H-indole-2-carboxamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-76f54e5997174ebba6fcb30d046831ad
Source noteuspto-grants-2005_03