HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichlorobenzylidenemalononitrile → 5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-pyrrolidin-1-yl-pyrimidin-4-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichlorobenzylidenemalononitrile | HCID 18089 | — |
| Reactant | Pyrrolidine-1-carboximidamide | HCID 2794597 | — |
| Product | 5-Aminomethyl-6-(2,4-dichloro-phenyl)-2-pyrrolidin-1-yl-pyrimidin-4-ylamine | HCID 10125885 | — |
Reaction Steps
The title compound, MS: m/e=337.8 (M+), was prepared from pyrrolidine-1-carboxamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06867205B2 |
| Source dataset | uspto-grants-2005_03 |
| ORD ID | ord-48da1a1ee36a48959c27585c6b19fa88 |
| Source note | uspto-grants-2005_03 |