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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983850Generated: October 25, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-2-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-4-amine

https://huagongshe.com/reaction/983850

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
Reactant4-ChlorobenzamidineHCID 203437—
Product5-(Aminomethyl)-2-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-4-amineHCID 10309373—

Reaction Steps

The title compound, MS: m/e=377.8 (M+), was prepared from 4-chloro-benzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-368b126c17b8408596c5ed1b8f75bccd
Source noteuspto-grants-2005_03